statin

S1T1A1T1I1N1
/ˈstætɪn/

noun

Any of a class of drugs, the HMG-CoA reductase inhibitors, that lower the amount of cholesterol in the blood by inhibiting an enzyme involved in its biosynthesis.

Similar
lipid-lowering medicinelipid-lowering medicationstatin drug
Less commonFirst used 1980sScrabble 6

Meanings

nounstatin (plural statins)

plural statins

  1. medicineAny of a class of drugs, the HMG-CoA reductase inhibitors, that lower the amount of cholesterol in the blood by inhibiting an enzyme involved in its biosynthesis.First known use 1980s

    Among the latest are reports of the ability of several leading statins to reduce deaths from common cancers and blunt the decline of memory with age.

    2020 September 21, Jane E. Brody, “For Older People, Reassuring News in the Statin Debate”, in The New York Times, archived from the original on 07 Nov 2020
    1 more example

    The researchers found that statins were likely to provide benefits at a substantially higher health risk than expected and that those risk levels were lower for atorvastatin and rosuvastatin than for simvastatin and pravastatin. […] Yet some of the statin side effects mentioned in the study have not been proved in the scientific literature or are exaggerated and could cause unnecessary worry, he said.

    2018 December 3, Jacqueline Howard, “Are statins overprescribed? Why the risks and benefits are so complex”, in CNN
  2. endocrinologyAn inhibiting hormone: a hormone that is involved primarily in inhibiting the release of another hormone.First known use 1970s

    Antonyms: liberin, releasing hormone

Synonyms & antonyms

nounAn inhibiting hormone: a hormone that is involved primarily in inhibiting the release of another hormone.

More synonyms by meaning

nouna medicine that lowers blood cholesterol levels by inhibiting HMG-CoA reductase

Similar
lipid-lowering medicinelipid-lowering medicationstatin drug

Synonym sets from Open English WordNet, CC BY 4.0.

Origin

From the suffix -statin, which was used for inhibiting hormone names before it was used for HMG-CoA reductase inhibitor drug names (but, like statin, has since become much better known in the latter sense).

Full word history & related roots →

Translations

Chinese Mandarin 他汀類藥物 /他汀类药物
  • 他汀類藥物 /他汀类药物 (tātīnglèi yàowù)any of a class of drugs
Finnish statiini
  • statiiniany of a class of drugs
French statine
  • statineany of a class of drugs
German Statin
  • Statinany of a class of drugs
Spanish estatina
  • estatinaany of a class of drugs
Turkish statin
  • statinany of a class of drugs

Rhymes & wordplay

Sounds the same

Anagrams

Cite this entry
APA

statin. (n.d.). In WatkinsX Dictionary. Retrieved November 3, 2026, from https://dictionary.watkinsx.com/word/statin

MLA

“statin.” WatkinsX Dictionary, https://dictionary.watkinsx.com/word/statin. Accessed November 3, 2026.

Chicago

WatkinsX Dictionary, s.v. “statin,” accessed November 3, 2026, https://dictionary.watkinsx.com/word/statin.

Source: statin on Wiktionary, CC BY-SA 4.0.