superrepressor

plural superrepressors

1. biologyA particularly effective repressor

   For this end, we crossed IKK MyHC animals with animals expressing a mutated form of IκBα -(IκBα (S32A, S36A, Y42F) ), which is impervious to phosphorylation-induced degradation and thus acts as a superrepressor of NF-κB signaling[11 ].

   2015 November 6, “Cardiac-Specific Activation of IKK2 Leads to Defects in Heart Development and Embryonic Lethality”, in PLOS ONE, →DOI