tretinoin

T1R1E1T1I1N1O1I1N1
UK/tɹəˈtɪn.əʊ.ɪn/US/tɹəˈtɪn.oʊ.ɪn/

noun

The all-trans isomer of retinoic acid that is applied to the skin to treat severe acne and reduce facial wrinkles, roughness, and pigmented spots, and taken orally as a chemotherapy drug for acute promyelocytic leukemia.

Similar
all-trans retinoic acidATRAtret
OriginEnglish retino(ic acid) ← Latin trans- ← Proto-Italic *trāns- →
UncommonScrabble 9
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Meanings

nountretinoin (usually uncountable, plural tretinoins)

plural tretinoins

  1. uncountableusuallychemistryThe all-trans isomer of retinoic acid that is applied to the skin to treat severe acne and reduce facial wrinkles, roughness, and pigmented spots, and taken orally as a chemotherapy drug for acute promyelocytic leukemia.

    Synonyms: all-trans retinoic acid, ATRA, tret

Synonyms & antonyms

nounThe all-trans isomer of retinoic acid that is applied to the skin to treat severe acne and reduce facial wrinkles, roughness, and pigmented spots, and taken orally as a chemotherapy drug for acute promyelocytic leukemia.

Similar
all-trans retinoic acidATRAtret

Origin

  1. Proto-Indo-European*terh₂-
  2. Proto-Indo-European*térh₂t
  3. Proto-Indo-European*tr̥h₂ónts
  4. Proto-Indo-European*tr̥h₂n̥ts
  5. Proto-Italic*trāns
  6. Proto-Italic*trāns-
  7. Latintrans-
  8. Englishtr(ans)-
  9. Englishretino(ic acid)
  10. Englishtretinoin

From tr(ans)- + retino(ic acid) + -in.

Full word history & related roots →
Cite this entry
APA

tretinoin. (n.d.). In WatkinsX Dictionary. Retrieved November 4, 2026, from https://dictionary.watkinsx.com/word/tretinoin

MLA

“tretinoin.” WatkinsX Dictionary, https://dictionary.watkinsx.com/word/tretinoin. Accessed November 4, 2026.

Chicago

WatkinsX Dictionary, s.v. “tretinoin,” accessed November 4, 2026, https://dictionary.watkinsx.com/word/tretinoin.

Source: tretinoin on Wiktionary, CC BY-SA 4.0.