ultratoxic

This ultratoxic action of the toxin is apparent whether it be in the form of tuberculin, or as a bacillary emulsion in which the particles have retained their acid-fast property. This increased toxicity of the tuberculous toxin when injected into the brain seems inexplicable according to Wolff-Eisner's theory. The toxin would certainly come more rapidly into contact with the lysin than if injected subcutaneously, but this should also apply to intravenous injections. Experience proves that the toxic effect of intracerebral injections are more marked than is that of intravenous injections.

1911, Halliday Sutherland, Mary Leeds, The Control and Eradication of Tuberculosis: A Series of International Studies by Many Authors, W. Green & Sons, page 112