uridinyl

plural uridinyls

1. especiallyin compoundsuncountableusuallychemistryA univalent radical derived from uridine.

   Dimeric uridinyl derivatives synthesized by us did not exhibit significant activity.

   2015 August, Katarzyna Kral, Tadeusz Bieg, Urszula Nawrot, Katarzyna Włodarczyk, Anna Lalik, Przemys ław, HahnaIlona Wandzik, “New monomeric and dimeric uridinyl derivatives as inhibitors of chitin synthase”, in Bioorganic Chemistry, volume 61

   3 more examples

   Y is OH; Z is CH₂OH, CH₃ or H; B is 1-cytosinyl, 9-adenyl, 9-guanyl, 1-uridinyl or 1-thymidinyl provided that if n = 1 then B is not 1-thymidinyl;

   1998, Official Gazette of the United States Patent and Trademark Office, volume 1211, number 3, page 2924

   The uridinyl group is coordinated by residues Gln162, Gly191 and Gly87 whereas the glucose portion of the molecule is coordinated by Asn220, Gly258, Glu271, Asn293 and Leu85.

   2018 March 1, Camila A. Cotrim, Jose Sergio M. Soares, Bostjan Kobe, Marcelo Menossi, “Crystal structure and insights into the oligomeric state of UDP-glucose pyrophosphorylase from sugarcane”, in PLOS1

   Furthermore, pseudo uridinyl substitution of the uridinyl moiety for three inhibitors (68e, 65b, and 65e) exhibited comparable activity to the parent uracil derivatives.

   2020 September 15, Christine A. Arbour, Barbara Imperiali, “Uridine natural products: Challenging targets and inspiration for novel small molecule inhibitors”, in Bioorganic & Medicinal Chemistry, volume 28, number 18

2. broadlycountableusuallychemistryA uridinyl group.

   The molecule had two acetyls, four methyls, and three uridinyls attached to its backbone.