what's up with

phrase

What's wrong with; what's the problem or matter with. Said to express that the behaviour of someone, or operation of something, is out of the ordinary or problematic.

“What’s up with you?”

Similar
what's withwhat's the deal withwhat's the matter withwhat's the story withwhat's eating
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Meanings

phrasewhat's up with ...?
  1. colloquialWhat's wrong with; what's the problem or matter with. Said to express that the behaviour of someone, or operation of something, is out of the ordinary or problematic.

    What’s up with you?

    1 more example

    What the hell's up with this stupid computer now?!

    Synonyms: what's with, what's the deal with, what's the matter with, what's the story with, what's eating

  2. colloquialUsed to express disbelief or curiosity.

    What’s up with all this new music they’re playing?

    1 more example

    They raised my electricity rates again. What’s up with that?

  3. colloquial(The thing that is) the problem or issue with.

    I'll tell you what's up with the Government!

Synonyms & antonyms

phraseWhat's wrong with; what's the problem or matter with. Said to express that the behaviour of someone, or operation of something, is out of the ordinary or problematic.

Similar
what's withwhat's the deal withwhat's the matter withwhat's the story withwhat's eating

Translations

Danish hvad sker der for
  • hvad sker der forused to express disbelief or curiosity
Icelandic hvað er málið með
  • hvað er málið meðused to express disbelief or curiosity
Italian cos'ha che non va?, cosa c'è che non va in
  • cos'ha che non va?said to express a person's behavior is out of the ordinary
  • cosa c'è che non va insaid to express a person's behavior is out of the ordinary
Polish co jest z?, o co chodzi z?
  • co jest z?said to express a person's behavior is out of the ordinary
  • o co chodzi z?used to express disbelief or curiosity
Romanian ce s-a întâmplat cu...
  • ce s-a întâmplat cu...used to express disbelief or curiosity
Spanish qué pasa/ocurre/sucede con
  • qué pasa/ocurre/sucede consaid to express a person's behavior is out of the ordinary
Cite this entry
APA

what's up with. (n.d.). In WatkinsX Dictionary. Retrieved November 5, 2026, from https://dictionary.watkinsx.com/word/what's%20up%20with

MLA

“what's up with.” WatkinsX Dictionary, https://dictionary.watkinsx.com/word/what's%20up%20with. Accessed November 5, 2026.

Chicago

WatkinsX Dictionary, s.v. “what's up with,” accessed November 5, 2026, https://dictionary.watkinsx.com/word/what's%20up%20with.

Source: what's up with on Wiktionary, CC BY-SA 4.0.