The story
From narcot(ic) + -ize.
First known use, by meaning
- from 16th c. To use a narcotic in order to make (someone) drowsy or insensible; to anesthetize, to drug.
- from 19th c. To dull the senses of (a person, place etc.).
- from 19th c. To make into a narcotic.
Etymology from Wiktionary, CC BY-SA 4.0.