Etymology

unefficacious

U1N1E1F4F4I1C3A1C3I1O1U1S1

Today it means: Not efficacious. Full definition →

English efficacious ← Old French efficacieux ← Latin efficāx
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The story

  1. Proto-Indo-European*né
  2. Proto-Indo-European*n̥-
  3. Proto-Germanic*un-
  4. Proto-West Germanic*un-
  5. Old Englishun-
  6. Middle Englishun-
  7. Englishun-
  8. Latinefficāx
  9. Old Frenchefficacieux
  10. Englishefficacious
  11. English todayunefficacious

From un- + efficacious.

Etymology from Wiktionary, CC BY-SA 4.0.