Doebner modification

proper noun

A variant of Knoevenagel condensation in which one of the withdrawing groups on the nucleophile is a carboxylic acid, and the condensation product undergoes a subsequent decarboxylation step, the base being pyridine.

Meanings

proper nounthe Doebner modification
  1. chemistryA variant of Knoevenagel condensation in which one of the withdrawing groups on the nucleophile is a carboxylic acid, and the condensation product undergoes a subsequent decarboxylation step, the base being pyridine.

    Synonyms: Doebner condensation

Synonyms & antonyms

proper nounA variant of Knoevenagel condensation in which one of the withdrawing groups on the nucleophile is a carboxylic acid, and the condensation product undergoes a subsequent decarboxylation step, the base being pyridine.

Origin

Named after O. Doebner, who published on the topic in 1902.

Full word history & related roots →
Cite this entry
APA

Doebner modification. (n.d.). In WatkinsX Dictionary. Retrieved November 3, 2026, from https://dictionary.watkinsx.com/word/Doebner%20modification

MLA

“Doebner modification.” WatkinsX Dictionary, https://dictionary.watkinsx.com/word/Doebner%20modification. Accessed November 3, 2026.

Chicago

WatkinsX Dictionary, s.v. “Doebner modification,” accessed November 3, 2026, https://dictionary.watkinsx.com/word/Doebner%20modification.

Source: Doebner modification on Wiktionary, CC BY-SA 4.0.