Knoevenagel condensation

noun

The nucleophilic addition of an active hydrogen compound to a carbonyl group followed by a dehydration reaction in which a molecule of water is eliminated. The product is often an α,β-unsaturated ketone (a conjugated enone).

Meanings

nounKnoevenagel condensation (countable and uncountable, plural Knoevenagel condensations)

plural Knoevenagel condensations

  1. countableuncountablechemistryThe nucleophilic addition of an active hydrogen compound to a carbonyl group followed by a dehydration reaction in which a molecule of water is eliminated. The product is often an α,β-unsaturated ketone (a conjugated enone).

    Synonyms: Knoevenagel reaction

Synonyms & antonyms

nounThe nucleophilic addition of an active hydrogen compound to a carbonyl group followed by a dehydration reaction in which a molecule of water is eliminated. The product is often an α,β-unsaturated ketone (a conjugated enone).

Origin

Named after German chemist Emil Knoevenagel.

Full word history & related roots →
Cite this entry
APA

Knoevenagel condensation. (n.d.). In WatkinsX Dictionary. Retrieved November 5, 2026, from https://dictionary.watkinsx.com/word/Knoevenagel%20condensation

MLA

“Knoevenagel condensation.” WatkinsX Dictionary, https://dictionary.watkinsx.com/word/Knoevenagel%20condensation. Accessed November 5, 2026.

Chicago

WatkinsX Dictionary, s.v. “Knoevenagel condensation,” accessed November 5, 2026, https://dictionary.watkinsx.com/word/Knoevenagel%20condensation.

Source: Knoevenagel condensation on Wiktionary, CC BY-SA 4.0.