spiro

1. attributiveuncountablechemistryA polycyclic compound or system that contains a single atom as the only common member of two rings.

1. abbreviationclippinguncountabletransgender slangClipping of spironolactone.

   After trying everything short of Accutane, she finally found her magic combo of spironolactone and hormonal birth control. “Birth control and spiro were my dream duo,” she says. “They knocked out my acne, my skin was flawless, but I had to have both.”

   2022 January 31, Bella Cacciatore, “How Pregnancy and Social Media Helped Kara Nesvig’s Hormonal Acne”, in Glamour

   2 more examples

   I was on estradiol tablets, finasteride, micronized progesterone, and spironolactone. I had an orchiectomy and have been taken off of progesterone and spiro. As far as changes to my body, they have been very miniscule in comparison to a person half my age. The most changes have been in my face.

   2022, Laura Erickson-Schroth, editor, Trans Bodies, Trans Selves, 2nd edition, Oxford University Press, →ISBN, page 315

   Important to keep in mind: It usually takes up to three months to see a difference with tretinoin. So don’t expect miracles in a matter of a few weeks. However! Because I had been using tret previously, it really was like I just added the tranexamic acid and topical spiro to my routine.

   2024 September 24, Beth Gillette, “I Tested Apostrophe, and I’ll Never Get Acne Meds From My Derm’s Office Again”, in Cosmopolitan

plural Spiros

1. A surname.
2. A male given name from Greek.