spironolactone

S1P3I1R1O1N1O1L1A1C3T1O1N1E1
UK/ˌspʌɪ.ɹən.ə(ʊ)ˈlæk.təʊn/US/ˌspaɪ.ɹən.oʊˈlækˌtoʊn/US/spɪˌɹoʊ.nəˈlækˌtoʊn/US/ˌspɪɚ.ə.nəˈlæk.toʊn/

noun

A steroid drug which acts as an antimineralocorticoid (for which purpose it is used in the treatment of certain types of edema and hypertension) and an antiandrogen (for which purpose it is used as part of some types of hormone therapy, especially for transgender women).

Similar
spiroAldactone
UncommonScrabble 18

Meanings

nounspironolactone (uncountable)
  1. uncountablemedicineA steroid drug which acts as an antimineralocorticoid (for which purpose it is used in the treatment of certain types of edema and hypertension) and an antiandrogen (for which purpose it is used as part of some types of hormone therapy, especially for transgender women).

    Synonyms: spiro

Synonyms & antonyms

nounA steroid drug which acts as an antimineralocorticoid (for which purpose it is used in the treatment of certain types of edema and hypertension) and an antiandrogen (for which purpose it is used as part of some types of hormone therapy, especially for transgender women).

Similar

More synonyms by meaning

nouna synthetic corticosteroid (trade name Aldactone) used to treat hypertension

Similar
Aldactone
Broader
corticosteroidcorticoidadrenal cortical steroidantihypertensiveantihypertensive drug

Synonym sets from Open English WordNet, CC BY 4.0.

Origin

  1. Proto-Indo-European*sper-
  2. Proto-Indo-European*sper-yeh₂-
  3. Ancient Greekσπεῖρα (speîra)
  4. Latinspīra
  5. Englishspiro-
  6. GermanKeton
  7. Englishketone
  8. Latinlac
  9. Englishlacto-
  10. Englishlactone
  11. Englishspironolactone

From spiro- + -one + -o- + lactone.

Full word history & related roots →

Translations

Chinese Mandarin 螺內酯 /螺内酯
  • 螺內酯 /螺内酯 (luónèizhǐ)Translations
French spironolactone
  • spironolactoneTranslations

Rhymes & wordplay

Rhymes with spironolactone

All rhymes →
Cite this entry
APA

spironolactone. (n.d.). In WatkinsX Dictionary. Retrieved November 4, 2026, from https://dictionary.watkinsx.com/word/spironolactone

MLA

“spironolactone.” WatkinsX Dictionary, https://dictionary.watkinsx.com/word/spironolactone. Accessed November 4, 2026.

Chicago

WatkinsX Dictionary, s.v. “spironolactone,” accessed November 4, 2026, https://dictionary.watkinsx.com/word/spironolactone.

Source: spironolactone on Wiktionary, CC BY-SA 4.0.