Van Wyk and Grumbach syndrome

noun

A medical condition involving hypothyroidism, precocious puberty (with delayed bone age and lack of pubic hair), and ovarian cysts in pre- and post-pubertal girls or macroorchidism in boys.

Meanings

nounVan Wyk and Grumbach syndrome (uncountable)
  1. uncountableA medical condition involving hypothyroidism, precocious puberty (with delayed bone age and lack of pubic hair), and ovarian cysts in pre- and post-pubertal girls or macroorchidism in boys.

Origin

Described in 1960 by Van Wyk and Melvin M. Grumbach.

Full word history & related roots →
Cite this entry
APA

Van Wyk and Grumbach syndrome. (n.d.). In WatkinsX Dictionary. Retrieved November 5, 2026, from https://dictionary.watkinsx.com/word/Van%20Wyk%20and%20Grumbach%20syndrome

MLA

“Van Wyk and Grumbach syndrome.” WatkinsX Dictionary, https://dictionary.watkinsx.com/word/Van%20Wyk%20and%20Grumbach%20syndrome. Accessed November 5, 2026.

Chicago

WatkinsX Dictionary, s.v. “Van Wyk and Grumbach syndrome,” accessed November 5, 2026, https://dictionary.watkinsx.com/word/Van%20Wyk%20and%20Grumbach%20syndrome.

Source: Van Wyk and Grumbach syndrome on Wiktionary, CC BY-SA 4.0.