acantholysis

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UK/æˌkænˈθɒ.lɪs.ɪs/US/æˌkænˈθɑ.lə.sɪs/

noun

The loss of intercellular connections, resulting in loss of cohesion between keratinocytes, seen in diseases such as pemphigus vulgaris.

Scrabble 20

Meanings

nounacantholysis (usually uncountable, plural acantholyses)

plural acantholyses

  1. uncountableusuallymedicineThe loss of intercellular connections, resulting in loss of cohesion between keratinocytes, seen in diseases such as pemphigus vulgaris.

Origin

From acanth- (“spine”) + -lysis (“destruction”).

Full word history & related roots →

Translations

Portuguese acantólise
  • acantóliseloss of intercellular connections

Rhymes & wordplay

Rhymes with acantholysis

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Cite this entry
APA

acantholysis. (n.d.). In WatkinsX Dictionary. Retrieved November 3, 2026, from https://dictionary.watkinsx.com/word/acantholysis

MLA

“acantholysis.” WatkinsX Dictionary, https://dictionary.watkinsx.com/word/acantholysis. Accessed November 3, 2026.

Chicago

WatkinsX Dictionary, s.v. “acantholysis,” accessed November 3, 2026, https://dictionary.watkinsx.com/word/acantholysis.

Source: acantholysis on Wiktionary, CC BY-SA 4.0.