centroblast

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/ˈsɛntɹəblæst//-blɑːst/

noun

An activated B cell that is enlarged with multiple eccentric nucleoli and proliferating in the germinal center of a secondary lymphoid follicle, after stimulation by follicular dendritic cell cytokines and helper T cells.

Scrabble 15
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Meanings

nouncentroblast (plural centroblasts)

plural centroblasts

  1. anatomyAn activated B cell that is enlarged with multiple eccentric nucleoli and proliferating in the germinal center of a secondary lymphoid follicle, after stimulation by follicular dendritic cell cytokines and helper T cells.

    Therefore we proposed the term centroblast instead of germinoblast and the term centrocyte instead of germinocyte.

    1975, K Lennert, “Morphology and classification of malignant lymphomas and so-called reticuloses”, in Malignant Lymphomas of the Nervous System

Origin

From centro- + -blast.

Full word history & related roots →
Cite this entry
APA

centroblast. (n.d.). In WatkinsX Dictionary. Retrieved November 2, 2026, from https://dictionary.watkinsx.com/word/centroblast

MLA

“centroblast.” WatkinsX Dictionary, https://dictionary.watkinsx.com/word/centroblast. Accessed November 2, 2026.

Chicago

WatkinsX Dictionary, s.v. “centroblast,” accessed November 2, 2026, https://dictionary.watkinsx.com/word/centroblast.

Source: centroblast on Wiktionary, CC BY-SA 4.0.