chromans

Next, a competing functional group (OH in 4-mercaptophenol 2 i) was investigated, as phenols have been shown to form chromans or Friedel–Crafts allylation products under gold-catalysis with allylic alcohols. Pleasingly, the reaction proceeds chemoselectively at the thiophenol site, although the yield is somewhat lower than with other thiophenols (49 %, entry 9).

2014 July 30, Lorena Herkert et al., “Gold(I)-Catalysed Direct Thioetherifications Using Allylic Alcohols: an Experimental and Computational Study”, in Chemistry (Weinheim an Der Bergstrasse, Germany), volume 20, →DOI