defasciculate

present singular third person defasciculates · participle present defasciculating · participle past defasciculated · past defasciculated

1. intransitiveOf an axon, to separate from a fascicle.

   The second is called "parallel bypass" where SNb defasciculates but continues to parallel the ISN. The third is termed the "stall" where SNb defasciculates and stops on its way to the muscle field.

   2001, Huidy Shu, A molecular genetic analysis of axon guidance in Drosophila melanogaster: signal transduction and receptor diversity

   1 more example

   In Slit2 mutant mice, motor nerves prematurely defasciculate into smaller bundlers in various muscles, unlike those in wild type that stay in compact fascicle until they reach the middle of muscle fibers.

   2015, Haitao Wu et al., “Slit2 as a β-catenin/Ctnnb1-dependent retrograde signal for presynaptic differentiation”, in eLife, volume 4, →DOI