dicyclohexylcarbodiimide

plural dicyclohexylcarbodiimides · abbreviation DCC

1. countableuncountablechemistryA chemical reagent commonly used in organic synthesis to activate carboxylic acids so they can form bonds with amines, especially to create amide bonds in peptide synthesis. It works as a coupling agent that helps join molecules together, producing dicyclohexylurea as a byproduct.

   1 more example

   The reaction was initiated by adding a solution containing 50 mmol/L potassium phosphate (pH 7.0), 5 mmol/L MgSO 4 and carbonyl cyanide m -chlorophenylhydrazone (CCCP, final 20 μ mol/L) or dicyclohexylcarbodiimide (DCCD, final 50 μ mol/L), and [ 3 H] l -alanine (38 Ci mmol −1, Moravek Biochemical, Brea, CA, USA; final, 0.54 μ mol/L).

   2015 June 13, Seryoung Kim et al., “Characterization of the l-alanine exporter AlaE of Escherichia coli and its potential role in protecting cells from a toxic-level accumulation of l-alanine and its derivatives”, in MicrobiologyOpen, volume 4, →DOI