diethylstilbestrol

US/daɪˌɛθ.əl.stɪlˈbɛˌstɹɔl/

noun

A synthetic estrogen drug C₁₈H₂₀O₂ used formerly to prevent miscarriage or premature delivery in humans and to promote growth in livestock. The medical use of diethystilbestrol was discontinued in the U.S. during the early 1970s due to its association with serious side effects (such as reproductive tract abnormalities and increased rates of infertility) in offspring exposed to the drug while developing in the uterus. It is no longer commercially available in the U.S. and its use is currently limited to specially compounded formulations for veterinary care.

UncommonScrabble 27

Meanings

noundiethylstilbestrol (countable and uncountable, plural diethylstilbestrols, abbreviation DES)

plural diethylstilbestrols · abbreviation DES · alternative UK diethylstilboestrol

  1. countableuncountablechemistryA synthetic estrogen drug C₁₈H₂₀O₂ used formerly to prevent miscarriage or premature delivery in humans and to promote growth in livestock. The medical use of diethystilbestrol was discontinued in the U.S. during the early 1970s due to its association with serious side effects (such as reproductive tract abnormalities and increased rates of infertility) in offspring exposed to the drug while developing in the uterus. It is no longer commercially available in the U.S. and its use is currently limited to specially compounded formulations for veterinary care.

    In 1971, yet another such study identified an even more unusual carcinogen, a synthetic hormonal medicine called diethylstilbestrol.

    2010, Siddhartha Mukherjee, The Emperor of All Maladies, Fourth Estate (2011), page 277

    Synonyms: stilbestrol

Synonyms & antonyms

nounA synthetic estrogen drug C₁₈H₂₀O₂ used formerly to prevent miscarriage or premature delivery in humans and to promote growth in livestock. The medical use of diethystilbestrol was discontinued in the U.S. during the early 1970s due to its association with serious side effects (such as reproductive tract abnormalities and increased rates of infertility) in offspring exposed to the drug while developing in the uterus. It is no longer commercially available in the U.S. and its use is currently limited to specially compounded formulations for veterinary care.

More synonyms by meaning

nouna potent estrogen used in medicine and in feed for livestock and poultry

Synonym sets from Open English WordNet, CC BY 4.0.

Origin

Translations

Chinese Mandarin 己烯雌酚
  • 己烯雌酚 (jǐxīcífēn)estrogen drug
Cite this entry
APA

diethylstilbestrol. (n.d.). In WatkinsX Dictionary. Retrieved November 4, 2026, from https://dictionary.watkinsx.com/word/diethylstilbestrol

MLA

“diethylstilbestrol.” WatkinsX Dictionary, https://dictionary.watkinsx.com/word/diethylstilbestrol. Accessed November 4, 2026.

Chicago

WatkinsX Dictionary, s.v. “diethylstilbestrol,” accessed November 4, 2026, https://dictionary.watkinsx.com/word/diethylstilbestrol.

Source: diethylstilbestrol on Wiktionary, CC BY-SA 4.0.