dysregulate

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verb

To cause a dysfunctional level of an activity or chemical in an organism by disrupting normal function of a regulatory mechanism.

OriginEnglish regulate ← New Latin dys- →
Scrabble 16
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Meanings

verbdysregulate (third-person singular simple present dysregulates, present participle dysregulating, simple past and past participle dysregulated)

present singular third person dysregulates · participle present dysregulating · participle past dysregulated · past dysregulated

  1. biologyTo cause a dysfunctional level of an activity or chemical in an organism by disrupting normal function of a regulatory mechanism.

    What, beyond abnormal, dysregulated cell division, was the common pathophysiological mechanism underlying cancer?

    2010, Siddhartha Mukherjee, The Emperor of All Maladies, Fourth Estate (2011), page 285

Origin

  1. New Latindys-
  2. Englishdys-
  3. Englishregulate
  4. Englishdysregulate

From dys- + regulate.

Full word history & related roots →
Cite this entry
APA

dysregulate. (n.d.). In WatkinsX Dictionary. Retrieved November 2, 2026, from https://dictionary.watkinsx.com/word/dysregulate

MLA

“dysregulate.” WatkinsX Dictionary, https://dictionary.watkinsx.com/word/dysregulate. Accessed November 2, 2026.

Chicago

WatkinsX Dictionary, s.v. “dysregulate,” accessed November 2, 2026, https://dictionary.watkinsx.com/word/dysregulate.

Source: dysregulate on Wiktionary, CC BY-SA 4.0.