endotype

plural endotypes

1. medicineA subtype of a pathological condition

   2 more examples

   The phenotype is useful in treatment planning while the endotype provides insight in pathophysiological mechanisms of CRS. Therefore, investigations of the pathogenesis and the factors amplifying mucosal inflammation are therefore, of crucial importance for the development of new diagnostic and therapeutic tools.

   2015 August 15, Thanit Chalermwatanachai, Nan Zhang, Gabriele Holtappels, Claus Bachert, “Association of Mucosal Organisms with Patterns of Inflammation in Chronic Rhinosinusitis”, in PLOS ONE, →DOI, archived from the original on 08 Nov 2020

   T2Rs are a novel target for asthma, CRS, and AD treatment independent of the inflammatory profile (type 2 or non–type 2) and could be the perfect example of a smart drug design starting from the endotype and theratype and extending through the drug development program. […] In the future, many new endotypes and theratypes particularly defined by treatment response will be introduced.

   2019 April, Ioana Agache, Cezmi A. Akdis, “Precision medicine and phenotypes, endotypes, genotypes, regiotypes, and theratypes of allergic diseases”, in Journal of Clinical Investigation, volume 129, number 4, →DOI, archived from the original on 04 Jun 2021, page 1499