haploinsufficiency

noun

The state of a diploid organism having only a single copy of a particular gene, the other copy being inactivated due to mutation

Opposite
triplosensitivity
OriginEnglish insufficiency ← Ancient Greek ᾰ̔πλόος (hăplóos) ← Proto-Hellenic *hə- →
Scrabble 36
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Meanings

nounhaploinsufficiency (countable and uncountable, plural haploinsufficiencies)

plural haploinsufficiencies

  1. countableuncountablebiologyThe state of a diploid organism having only a single copy of a particular gene, the other copy being inactivated due to mutation

Synonyms & antonyms

Opposite
triplosensitivity

Origin

  1. Proto-Indo-European*sem-
  2. Proto-Indo-European*sm̥-
  3. Proto-Hellenic*hə-
  4. Ancient Greekᾰ̔- (hă-)
  5. Ancient Greekᾰ̔πλόος (hăplóos)
  6. Englishhaplo-
  7. Englishinsufficiency
  8. Englishhaploinsufficiency

From haplo- + insufficiency.

Full word history & related roots →

Translations

Finnish haploinsuffisienssi
  • haploinsuffisienssiTranslations
Cite this entry
APA

haploinsufficiency. (n.d.). In WatkinsX Dictionary. Retrieved November 4, 2026, from https://dictionary.watkinsx.com/word/haploinsufficiency

MLA

“haploinsufficiency.” WatkinsX Dictionary, https://dictionary.watkinsx.com/word/haploinsufficiency. Accessed November 4, 2026.

Chicago

WatkinsX Dictionary, s.v. “haploinsufficiency,” accessed November 4, 2026, https://dictionary.watkinsx.com/word/haploinsufficiency.

Source: haploinsufficiency on Wiktionary, CC BY-SA 4.0.