hematin

plural hematins · alternative haematin · alternative hæmatin · alternative hematine · alternative haematine · alternative hæmatine

1. countableuncountablebiochemistryHemoglobin with iron in ferric state.

   A urinary pH of 5.6 or less causes myoglobin to dissociate into globin and hematin (Reilly & Salluzzo, 1990).

   2005, Sharon G. Childs, “Rhabdomyolysis”, in Orthopaedic Nursing, volume 24, number 6, →PMID, page 445

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   When the stain is of recent date, or supposed to be so, the red corpuscles should be particularly examined, and every care should be taken to preserve them without change. The stains must not be washed with water, so that the hæmatin may not be altered.

   1873 December 5, “The Examination of Blood-Stains”, in William Crookes, editor, The Chemical News and Journal of Physical Science, volume XXVIII, number 732, page 291

2. countableuncountablebiochemistryHemin.

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   This study was a multi-center, randomized, double-blind, placebo-controlled clinical trial in premenopausal women between 18 and 50 years old with cyclic (22 to 35 days) abnormal uterine bleeding in ≥4 of the last 6 menstrual cycles, menstrual blood loss ≥80 mL as measured by the alkaline hematin method over the first 8 days of menses, ≥1 discrete uterine fibroid of any size and location observable by transvaginal ultrasound, follicle-stimulating hormone ≤20 mIU/mL, and uterine volume ≤20 weeks by exam.

   2016 May 9, “Allergan and Richter Announce Positive Phase III Results for Ulipristal Acetate 5 and 10 mg in the Treatment of Uterine Fibroids”, in PR Newswire