hydroxychloroquine

More on Malaria: Sterling-Winthrop Research Institute reports a new, effective antimalarial. Called hydroxychloroquine, its activity (with experimental animals) is equal to that of chloroquine, but it is much safer in large doses. Hydroxychloroquine can be taken orally or by injection and is retained in the blood for a longer period of time than chloroquine.

1951, Chemical Week, volume 69, page 28

Seventy-five patients suffering from P. falciparum malaria were treated at Gressier, Haiti, with a single oral dose of hydroxychloroquine, which has the chemical structure 7-chloro-4 (4'-(N-ethyl-N-B-hydroxyethylamino)-1-methylbutylamino)-quinoline diphosphate.

1952, E. H. Loughlin, “The Treatment of Plasmodium falciparum Malaria with a Single Dose Antimalarial”, in Antibiotics and Chemotherapy, volume 2, number 4, page 171

Mr. [Donald] Trump’s recommendation of hydroxychloroquine, for the second day in a row at a White House briefing, was a striking example of his brazen willingness to distort and outright defy expert opinion and scientific evidence when it does not suit his agenda. […] And while many hospitals have chosen to use hydroxychloroquine in a desperate attempt to treat dying patients who have few other options, others have noted that it carries serious risks.

2020 April 5, “Ignoring Expert Opinion, Trump Again Promotes Use of Hydroxychloroquine”, in The New York Times, archived from the original on 12 Aug 2020