Meanings
nounhypermannosylation (uncountable)
- uncountableExcessive mannosylation
The Fc variants contained two mutations (C228S and C231S) in the hinge region to exclude Fc homodimerization by eliminating the natural disulfide bonds in the hinge region and an N297Q mutation to avoid yeast hypermannosylation by removing the N-linked glycosylation site in the CH2 domain.
2015 December 17, “Engineering of Immunoglobulin Fc Heterodimers Using Yeast Surface-Displayed Combinatorial Fc Library Screening”, in PLOS ONE, →DOI
Origin
Cite this entry
APA
hypermannosylation. (n.d.). In WatkinsX Dictionary. Retrieved November 3, 2026, from https://dictionary.watkinsx.com/word/hypermannosylation
MLA
“hypermannosylation.” WatkinsX Dictionary, https://dictionary.watkinsx.com/word/hypermannosylation. Accessed November 3, 2026.
Chicago
WatkinsX Dictionary, s.v. “hypermannosylation,” accessed November 3, 2026, https://dictionary.watkinsx.com/word/hypermannosylation.
Source: hypermannosylation on Wiktionary, CC BY-SA 4.0.