hypermethylation

noun

an increase in the epigenetic methylation of cytosine and adenosine residues in DNA.

Opposite
hypomethylation
OriginEnglish methylation ← Ancient Greek ῠ̔περ- (hŭper-) ← Proto-Hellenic *hupér →
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Meanings

nounhypermethylation (countable and uncountable, plural hypermethylations)

plural hypermethylations

  1. countableuncountablebiologyan increase in the epigenetic methylation of cytosine and adenosine residues in DNA.

Synonyms & antonyms

Opposite
hypomethylation

Origin

  1. Proto-Indo-European*úp
  2. Proto-Indo-European*upér
  3. Proto-Hellenic*hupér
  4. Ancient Greekῠ̔πέρ (hŭpér)
  5. Ancient Greekῠ̔περ- (hŭper-)
  6. Englishhyper-
  7. Englishmethylation
  8. Englishhypermethylation

From hyper- + methylation.

Full word history & related roots →
Cite this entry
APA

hypermethylation. (n.d.). In WatkinsX Dictionary. Retrieved November 3, 2026, from https://dictionary.watkinsx.com/word/hypermethylation

MLA

“hypermethylation.” WatkinsX Dictionary, https://dictionary.watkinsx.com/word/hypermethylation. Accessed November 3, 2026.

Chicago

WatkinsX Dictionary, s.v. “hypermethylation,” accessed November 3, 2026, https://dictionary.watkinsx.com/word/hypermethylation.

Source: hypermethylation on Wiktionary, CC BY-SA 4.0.