hypertrophy

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UK/haɪˈpɜː.tɹə.fi/US/haɪˈpɜɹ.tɹə.fi/

noun

An increase in the size of an organ or tissue due to the enlargement of its individual cells.

Less commonScrabble 27

Meanings

nounhypertrophy (countable and uncountable, plural hypertrophies)

plural hypertrophies

  1. countablemedicineAn increase in the size of an organ or tissue due to the enlargement of its individual cells.

    Ectopic chondrocyte hypertrophy has been demonstrated in OA, suggesting that the pathogenetical process involves a recapitulation of endochondral ossification [ 11 – 13 ].

    2010 January 29, Anita Woods et al., “Control of chondrocyte gene expression by actin dynamics: a novel role of cholesterol/Ror-α signalling in endochondral bone growth”, in Journal of Cellular and Molecular Medicine, volume 13, →DOI

    Antonyms: atrophy, hypotrophy, hyperplasia

    1. uncountablebodybuildingIncrease in muscle size through increased size of individual muscle cells; a result of weightlifting, and other exercise. It differs from muscle hyperplasia, which is the formation of new muscle cells.

      Antonyms: atrophy, hypotrophy, hyperplasia

verbhypertrophy (third-person singular simple present hypertrophies, present participle hypertrophying, simple past and past participle hypertrophied)

present singular third person hypertrophies · participle present hypertrophying · participle past hypertrophied · past hypertrophied

  1. intransitiveOf a tissue or organ, to increase in size.

    Antonyms: atrophy

  2. broadlyTo enlarge or extend.

    Like a well-exercised muscle, 'network' has hypertrophied into a master concept.

    2020, Merlin Sheldrake, Entangled Life, page 76
    1 more example

    But when text hypertrophies into a riot of contending inscripturations, we lose too much of what matters most in writing.

    2020 January 29, Douglas Groothuis, “Texts, Graphics, and Culture: On the Decline of Reading and Civilization”, in Douglas Groothuis, Ph.D.: Christian Philosopher and Apologist, archived from the original on 27 Jan 2023

    Antonyms: atrophy

Synonyms & antonyms

nounAn increase in the size of an organ or tissue due to the enlargement of its individual cells.

nounIncrease in muscle size through increased size of individual muscle cells; a result of weightlifting, and other exercise. It differs from muscle hyperplasia, which is the formation of new muscle cells.

verbOf a tissue or organ, to increase in size.

Opposite

verbTo enlarge or extend.

Opposite
Also see

Origin

  1. Ancient Greekὑπέρ“over, excessive”
  2. Frenchhypertrophie
  3. Englishhypertrophy

From French hypertrophie, from Ancient Greek ὑπέρ (hupér, “over, excessive”) + τροφή (trophḗ, “nourishment”), equivalent to hyper- + -trophy.

Full word history & related roots →

Translations

Catalan hipertròfia, hipertrofiar
  • hipertròfiaincrease in the size due to cell enlargement
  • hipertrofiarto increase in size
Chinese Mandarin 肥大
  • 肥大 (féidà)increase in the size due to cell enlargement
Dutch hypertrofie
  • hypertrofieincrease in the size due to cell enlargement
Esperanto hipertrofio
  • hipertrofioincrease in the size due to cell enlargement
Finnish hypertrofia
  • hypertrofiaincrease in the size due to cell enlargement
French hypertrophie, s’hypertrophier
  • hypertrophieincrease in the size due to cell enlargement
  • s’hypertrophierto increase in size
German Hypertrophie, hypertrophieren
  • Hypertrophieincrease in the size due to cell enlargement
  • hypertrophierento increase in size
Greek υπερτροφία, υπερτροφώ
  • υπερτροφία (ypertrofía)increase in the size due to cell enlargement
  • υπερτροφώ (ypertrofó)to increase in size
  • αυξάνω (afxáno)to increase in size
Indonesian hipertrofi
  • hipertrofiincrease in the size due to cell enlargement
Irish hipeartrófacht
  • hipeartrófachtincrease in the size due to cell enlargement
Italian ipertrofia
  • ipertrofiaincrease in the size due to cell enlargement
Japanese 肥大, 肥大する
  • 肥大 (hidai)increase in the size due to cell enlargement
  • 肥大する (hidai suru)to increase in size
Korean 비대
  • 비대 (bidae)increase in the size due to cell enlargement
Latin hypertrophia
  • hypertrophiaincrease in the size due to cell enlargement
Norwegian Bokmål hypertrofi
  • hypertrofiincrease in the size due to cell enlargement
Polish hipertrofia, przerost
  • hipertrofiaincrease in the size due to cell enlargement
  • przerostincrease in the size due to cell enlargement
Portuguese hipertrofia, hipertrofiar
  • hipertrofiaincrease in the size due to cell enlargement
  • hipertrofiarto increase in size
Romanian hipertrofie, hipertrofia
  • hipertrofieincrease in the size due to cell enlargement
  • hipertrofiato increase in size
Russian гипертрофи́я
  • гипертрофи́я (gipertrofíja)increase in the size due to cell enlargement
Spanish hipertrofia, hipertrofiarse
  • hipertrofiaincrease in the size due to cell enlargement
  • hipertrofiarseto increase in size
Swedish hypertrofi
  • hypertrofiincrease in the size due to cell enlargement
Vietnamese sự nở to
  • sự nở toincrease in the size due to cell enlargement
Cite this entry
APA

hypertrophy. (n.d.). In WatkinsX Dictionary. Retrieved November 2, 2026, from https://dictionary.watkinsx.com/word/hypertrophy

MLA

“hypertrophy.” WatkinsX Dictionary, https://dictionary.watkinsx.com/word/hypertrophy. Accessed November 2, 2026.

Chicago

WatkinsX Dictionary, s.v. “hypertrophy,” accessed November 2, 2026, https://dictionary.watkinsx.com/word/hypertrophy.

Source: hypertrophy on Wiktionary, CC BY-SA 4.0.