hypofunctional

H4Y4P3O1F4U1N1C3T1I1O1N1A1L1

adjective

Having a decreased function (especially of an endocrine gland)

Scrabble 27
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Meanings

adjectivehypofunctional (not comparable)
  1. not comparableHaving a decreased function (especially of an endocrine gland)

    Support for the hypofunctional (as opposed to activated) microglia model is largely based on morphological examination of IBA1-stained microglia in autopsy samples from aged humans [ 29 – 32 ], as currently there are no specific markers that recognize only degenerating/dystrophic microglia.

    2015 May 23, Adam D. Bachstetter et al., “Disease-related microglia heterogeneity in the hippocampus of Alzheimer’s disease, dementia with Lewy bodies, and hippocampal sclerosis of aging”, in Acta Neuropathologica Communications, volume 3, →DOI

Origin

From hypo- + functional.

Full word history & related roots →
Cite this entry
APA

hypofunctional. (n.d.). In WatkinsX Dictionary. Retrieved November 2, 2026, from https://dictionary.watkinsx.com/word/hypofunctional

MLA

“hypofunctional.” WatkinsX Dictionary, https://dictionary.watkinsx.com/word/hypofunctional. Accessed November 2, 2026.

Chicago

WatkinsX Dictionary, s.v. “hypofunctional,” accessed November 2, 2026, https://dictionary.watkinsx.com/word/hypofunctional.

Source: hypofunctional on Wiktionary, CC BY-SA 4.0.