hypomethylation

H4Y4P3O1M3E1T1H4Y4L1A1T1I1O1N1

noun

a decrease in the epigenetic methylation of cytosine and adenosine residues in DNA

Opposite
hypermethylation
OriginEnglish methylation ← Ancient Greek ὑπο- (hupo-) ← Proto-Indo-European *upó →
Scrabble 31
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Meanings

nounhypomethylation (plural hypomethylations)

plural hypomethylations

  1. biologya decrease in the epigenetic methylation of cytosine and adenosine residues in DNA

Synonyms & antonyms

Opposite
hypermethylation

Origin

  1. Proto-Indo-European*upó
  2. Ancient Greekῠ̔πό (hŭpó)
  3. Ancient Greekὑπο- (hupo-)
  4. Englishhypo-
  5. Englishmethylation
  6. Englishhypomethylation

From hypo- + methylation.

Full word history & related roots →
Cite this entry
APA

hypomethylation. (n.d.). In WatkinsX Dictionary. Retrieved November 4, 2026, from https://dictionary.watkinsx.com/word/hypomethylation

MLA

“hypomethylation.” WatkinsX Dictionary, https://dictionary.watkinsx.com/word/hypomethylation. Accessed November 4, 2026.

Chicago

WatkinsX Dictionary, s.v. “hypomethylation,” accessed November 4, 2026, https://dictionary.watkinsx.com/word/hypomethylation.

Source: hypomethylation on Wiktionary, CC BY-SA 4.0.