phlebotonic

comparative more phlebotonic · superlative most phlebotonic

1. Affecting the tone of veins; that is, affecting the muscle tone of the smooth muscle in the walls of veins, thus influencing blood flow within the lumen.

   Synonyms: venotonic

plural phlebotonics

1. A substance (especially a drug) that is phlebotonic; a drug that modifies the tone of vein walls to treat venous insufficiency causing venous ulcers, hemorrhoids, or varicose veins.

   1 more example

   Phlebotonics are a heterogeneous class of drugs used to treat haemorrhoidal disease in the less severe stages of first and second-degree haemorrhoids, and during the thrombosis episodes. Although their true mechanism of action has not been well established, they are associated with strengthening of blood vessel walls, increasing venous tone, lymphatic drainage and normalizing capillary permeability. We considered twenty four studies for inclusion in this review. This review identified twenty randomised controlled trials enrolling a total of (2334) participants which compared an intervention using phlebotonics with a control intervention.

   2012, Perera N, Liolitsa D, Iype S, Croxford A, Yassin M, Lang P, Ukaegbu O, van Issum C, “Phlebotonics for haemorrhoids”, in Cochrane Database of Systematic Reviews, volume 15, number 8, →DOI, →PMID, page CD004322

   Synonyms: venotonic