Meanings
- not comparableConverted to a polyglutamate
MTX is actively accumulated in the liver where it is metabolized and stored in polyglutamated form, thus decreases folate levels by the inhibition of dihydrofolate reductase[5].
2015 July 25, Hend M. Tag, “Hepatoprotective effect of mulberry (Morus nigra) leaves extract against methotrexate induced hepatotoxicity in male albino rat”, in BMC Complementary and Alternative Medicine, volume 15, →DOI
Origin
Cite this entry
polyglutamated. (n.d.). In WatkinsX Dictionary. Retrieved November 3, 2026, from https://dictionary.watkinsx.com/word/polyglutamated
“polyglutamated.” WatkinsX Dictionary, https://dictionary.watkinsx.com/word/polyglutamated. Accessed November 3, 2026.
WatkinsX Dictionary, s.v. “polyglutamated,” accessed November 3, 2026, https://dictionary.watkinsx.com/word/polyglutamated.
Source: polyglutamated on Wiktionary, CC BY-SA 4.0.