prebiotic

P3R1E1B3I1O1T1I1C3
UK/pɹiːbaɪˈɒtɪk/

adjective

Before the advent of life.

UncommonFirst used 20th c.Scrabble 15

Meanings

adjectiveprebiotic (not comparable)
  1. not comparableBefore the advent of life.

    The amino acids which were formed through prebiotic reactions were surely chiral.

    2010, Giovanni Occhipinti, Prebiotic chemistry and the origin of life, →ISBN, page 30
    5 more examples

    There are three compelling reasons that suggest that the first set of prebiotic coding sequences to be translated were repeats of base oligomers, the numbers of bases in oligomeric units not being multiples of three.

    1986, Herrick Baltscheffsky, Hans Jornvall, Rudolf Rigler, Molecular Evolution of Life, →ISBN, page 43

    As a result, studies of uncoded peptide bond formation are founded in using NCAs as substrates (even when obtained as the reactive species of the non-prebiotic CDI activation) for mimicking prebiotic processes.

    2005, Peter Walde, Laurent Boiteau, Prebiotic Chemistry: From Simple Amphiphiles to Protocell Models, →ISBN

    The chemistry of cyanoacetylene, HC₃N, can lead in aqueous solution to the prebiotic synthesis of pyrimidines.

    2006, Bernard Barbier, Hervé Martin, Jacques Reisse, Lectures in Astrobiology: Vol I, →ISBN

    Home to 51 moons, including the prebiotic moon Anafiel, Dumah is a standard hydrogen-helium gas giant with violent surface winds exceeding 1,900 kph.

    2010, BioWare, Mass Effect 2 (Science Fiction), Redwood City: Electronic Arts, →OCLC, PC, scene: Dumah, Micah System

    Artificial prebiotic experiments were designed to mimic what might have occurred before life appeared.

    2014, Theodore R. Johnstone, Boundaries of Evolution, →ISBN
  2. not comparableOf a food, not digestible, but beneficial.

    The table below includes plant foods we consider to be prebiotic “stars” since they are the foods listed in the scientific literature as sources of prebiotics.

    2009, Jo Ann Hattner, Susan Anderes, Gut Insight, →ISBN, page 35
    3 more examples

    Evidence of the prebiotic properties of polydextrose (PDX), resistant maltodextrin (RMD), and other soluble fiber sources are slowly emerging, but the body of evidence is small compared to the gold standard of fructo oligosaccharides (FOS) and inulin.

    2011, Teresa M. Paeschke, William R. Aimutis, Nondigestible Carbohydrates and Digestive Health, →ISBN

    Our news journalists obtained a quote from the research from the University of Reading, “The ability to mediate a prebiotic modulation of gut microbiota has recently been suggested to have an inverse correlation with risk of cardiometabolic disease..."

    2013, Polysaccharides—Advances in Research and Application, →ISBN

    A growing body of evidence from in vitro, animal, and human studies suggests that the microbes in the gut are also reactive to coffee, and that coffee has prebiotic-like effects on the gut microbiome.

    2026 April 21, Serena Boscaini, Thomaz F. S. Bastiaanssen, Gerard M. Moloney, Federica Bergamo, Laila Zeraik, “Habitual coffee intake shapes the gut microbiome and modifies host physiology and cognition”, in Nature Communications, volume 17, number 1, →DOI, →ISSN
nounprebiotic (plural prebiotics)

plural prebiotics

  1. in pluralA substance in food that is hard to digest and promotes the growth of beneficial intestinal microorganisms.First known use 20th c.

    Prebiotics are nowhere near as well researched as probiotics, although there are already some sound results pertaining to how they work.

    2015, Giulia Enders, translated by David Shaw, Gut, Scribe, published 2016, page 240
    1 more example

    The table below includes plant foods we consider to be prebiotic “stars” since they are the foods listed in the scientific literature as sources of prebiotics.

    2009, Jo Ann Hattner, Susan Anderes, Gut Insight, →ISBN, page 35

Origin

  1. Proto-Indo-European*per-
  2. Proto-Indo-European*preh₂-
  3. Proto-Indo-European*préh₂i?
  4. Proto-Italic*prai
  5. Proto-Italic*prai-
  6. Latinprae-
  7. Middle Englishpre-
  8. Englishpre-
  9. Englishbiotic
  10. Englishprebiotic

From pre- + biotic.

Full word history & related roots →

Translations

German Präbiotikum
  • Präbiotikumfood substance
Italian prebiotico
  • prebioticofood substance
Polish prebiotyk
  • prebiotykfood substance
Portuguese prebiótico
  • prebióticofood substance
Spanish prebiótico
  • prebióticofood substance
Cite this entry
APA

prebiotic. (n.d.). In WatkinsX Dictionary. Retrieved November 2, 2026, from https://dictionary.watkinsx.com/word/prebiotic

MLA

“prebiotic.” WatkinsX Dictionary, https://dictionary.watkinsx.com/word/prebiotic. Accessed November 2, 2026.

Chicago

WatkinsX Dictionary, s.v. “prebiotic,” accessed November 2, 2026, https://dictionary.watkinsx.com/word/prebiotic.

Source: prebiotic on Wiktionary, CC BY-SA 4.0.