proto-oncogene

noun

A gene, promoting the specialization and division of normal cells, that could become an oncogene due to mutation.

Meanings

nounproto-oncogene (plural proto-oncogenes)

plural proto-oncogenes · alternative protooncogene

  1. biologyA gene, promoting the specialization and division of normal cells, that could become an oncogene due to mutation.

    Typically, proto-oncogenes are normal cellular genes that, when activated by mutation or overexpression, promote cancer.

    2010, Siddhartha Mukherjee, The Emperor of All Maladies, Fourth Estate (2011), page 534

Origin

  1. Proto-Indo-European*per-der.?
  2. Proto-Indo-European*pér
  3. Proto-Indo-European*pró
  4. Ancient Greekπρό (pró)
  5. Ancient Greekπρῶτος (prôtos)
  6. Ancient Greekπρωτο- (prōto-)
  7. Englishproto-
  8. Ancient Greekὄγκος (ónkos)
  9. New Latinonco-
  10. Englishonco-
  11. Englishgene
  12. Englishoncogene
  13. Englishproto-oncogene

From proto- + oncogene.

Full word history & related roots →

Translations

Finnish esisyöpägeeni, proto-onkogeeni
  • esisyöpägeenigene promoting the specialization and division of normal cells that could become an oncogene due to mutation
  • proto-onkogeenigene promoting the specialization and division of normal cells that could become an oncogene due to mutation
French proto-oncogène
  • proto-oncogènegene promoting the specialization and division of normal cells that could become an oncogene due to mutation
Hungarian protoonkogén
  • protoonkogéngene promoting the specialization and division of normal cells that could become an oncogene due to mutation
Italian protooncogene
  • protooncogenegene promoting the specialization and division of normal cells that could become an oncogene due to mutation
Cite this entry
APA

proto-oncogene. (n.d.). In WatkinsX Dictionary. Retrieved November 4, 2026, from https://dictionary.watkinsx.com/word/proto-oncogene

MLA

“proto-oncogene.” WatkinsX Dictionary, https://dictionary.watkinsx.com/word/proto-oncogene. Accessed November 4, 2026.

Chicago

WatkinsX Dictionary, s.v. “proto-oncogene,” accessed November 4, 2026, https://dictionary.watkinsx.com/word/proto-oncogene.

Source: proto-oncogene on Wiktionary, CC BY-SA 4.0.