scleroderma

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noun

A chronic systemic autoimmune disease characterized by hardening the skin or other organs through excessive deposits of collagen.

Less commonScrabble 16

Meanings

nounscleroderma (countable and uncountable, plural sclerodermas)

plural sclerodermas

  1. countableuncountablemedicineA chronic systemic autoimmune disease characterized by hardening the skin or other organs through excessive deposits of collagen.

    Synonyms: systemic sclerosis, scleroderm

Synonyms & antonyms

nounA chronic systemic autoimmune disease characterized by hardening the skin or other organs through excessive deposits of collagen.

More synonyms by meaning

nounan autoimmune disease that affects the blood vessels and connective tissue; fibrous connective tissue is deposited in the skin

Broader
autoimmune diseaseautoimmune disorder

Synonym sets from Open English WordNet, CC BY 4.0.

Origin

  1. Ancient Greekσκληρός“hard”
  2. New Latinsclēroderma
  3. Englishscleroderma

From New Latin sclēroderma, from Ancient Greek σκληρός (sklērós, “hard”) + δέρμα (dérma, “skin, hide”). By surface analysis, sclero- + -derma.

Full word history & related roots →

Translations

Finnish skleroderma
  • sklerodermadisease
Italian sclerodermia
  • sclerodermiadisease
Polish twardzina
  • twardzinadisease
Spanish esclerodermia
  • esclerodermiadisease
Cite this entry
APA

scleroderma. (n.d.). In WatkinsX Dictionary. Retrieved November 2, 2026, from https://dictionary.watkinsx.com/word/scleroderma

MLA

“scleroderma.” WatkinsX Dictionary, https://dictionary.watkinsx.com/word/scleroderma. Accessed November 2, 2026.

Chicago

WatkinsX Dictionary, s.v. “scleroderma,” accessed November 2, 2026, https://dictionary.watkinsx.com/word/scleroderma.

Source: scleroderma on Wiktionary, CC BY-SA 4.0.