sonidegib

S1O1N1I1D2E1G2I1B3

noun

A drug targeting the smoothened protein of the hedgehog signaling pathway, used for the treatment of basal cell carcinoma.

Scrabble 13

Meanings

nounsonidegib (uncountable)
  1. uncountablemedicineA drug targeting the smoothened protein of the hedgehog signaling pathway, used for the treatment of basal cell carcinoma.

    Among the inhibitors of the Hh pathway that interact directly with SMO, vismodegib and sonidegib are the two compounds approved by FDA in 2012 and 2015, respectively, for the treatment of basal cell carcinoma (BCC).

    2016 March 3, “Novel Acylguanidine Derivatives Targeting Smoothened Induce Antiproliferative and Pro-Apoptotic Effects in Chronic Myeloid Leukemia Cells”, in PLOS ONE, →DOI

Origin

Rhymes & wordplay

Anagrams

Cite this entry
APA

sonidegib. (n.d.). In WatkinsX Dictionary. Retrieved November 4, 2026, from https://dictionary.watkinsx.com/word/sonidegib

MLA

“sonidegib.” WatkinsX Dictionary, https://dictionary.watkinsx.com/word/sonidegib. Accessed November 4, 2026.

Chicago

WatkinsX Dictionary, s.v. “sonidegib,” accessed November 4, 2026, https://dictionary.watkinsx.com/word/sonidegib.

Source: sonidegib on Wiktionary, CC BY-SA 4.0.