spirometo-series

alternative spirometo series

1. A class of glycosphingolipids containing the sequence Galβ(1,4)Glcβ(1,3)Galβ-Cer (galactose, glucose, galactose, ceramide)

   So far, schisto- and spirometo-series glycosphingolipids have been only found in parasitic helminths

   2002, Bertram O. Fraser-Reid, Kuniaki Tatsuta, Joachim Thiem, Glycoscience: Chemistry and Chemical Biology I–III, →ISBN, page 2197

   2 more examples

   Structural analyses of the neutral glycosphgolipids from plerocercoids of the parasites Spirometra erinacei (Kawakami et al., 2993, 1995, 1996), Spirometra mansonoides (Singh et al., 1987), Diplogonoporus balaenopterae (Kawakami et al., 1997) as well as adult worms and plerocercoids of Diphyllobothrium hottai (Iriko et al., 2002) revealed the presence of a novel and so far unique biosynthetic series (spirometo-series) which is based on galactosylceramide and characterized by the monosaccharide sequence Gal(β1-4)Glc(β1-3)Galceramide (Fig. 21.6).

   2006, Aaron G. Maule, Nikki J. Marks, Parasitic Flatworms: Molecular Biology, Biochemistry, Immunology and Physiology, →ISBN

   AK97 was originally established for a spirometo-series parasitic glycosphingolipid having a characteristic trisaccharide structure [Galβ1-4(Fucα1-3)Glcβ-] (Kawakami et al. 1993) but strongly reacts also with SSEA-1 (Yanagisawa et al. 1999).

   2010 August, Hirokazu Yagi, Makoto Yanagisawa, Koichi Kato, Robert K Yu, “Lysosome-associated membrane protein 1 is a major SSEA-1-carrier protein in mouse neural stem cells”, in Glycobiology, volume 20, number 8