testicular dysgenesis syndrome

plural testicular dysgenesis syndromes

1. medicineA condition of the male reproductive system characterised by the presence of symptoms and disorders such as hypospadias, cryptorchidism, poor semen quality and testicular cancer.

   Collectively, these observed human phenotypes have been referred to as the testicular dysgenesis syndrome (TDS).

   2015, Gasry R. Klinefelter, “20: Male Reproductive Toxicology: Environmental Exposures versus Reproductive Competence”, in Mohamed Abou-Donia, editor, Mammalian Toxicology, Wiley, page 473

   2 more examples

   Recently, it has been suggested [78] that poor semen quality, testis cancer, undescended testis, and hypospadias are symptoms of one underlying entity: the testicular dysgenesis syndrome (TDS).

   2005, R. F. A. Weber, G. R. Dohle, J. C. Romijn, “Clinical Laboratory Evaluation of Male Subfertility”, in Gregory S. Makowski, editor, Advances in Clinical Chemistry, Volume 40, Elsevier (Academic Press), page 350

   Some of the risk factors for testicular dysgenesis syndrome are known, including premature birth, intrauterine growth restriction, maternal stress during pregnancy and some rare genetic disorders. However, these conditions cause only a small percentage of testicular dysgenesis syndrome cases.

   2015, Jackie Schwartz, Tracey Woodruff, “Chapter 20: The Risks to Reproductive Health and Fertility”, in Carole Joffe, Jennifer Reich, editors, Reproduction and Society: Interdisciplinary Readings, Taylor & Francis (Routledge), page 180