Meanings
nounvismodegib (uncountable)
- uncountablemedicineA drug targeting the smoothened protein of the hedgehog signaling pathway, used for the treatment of basal cell carcinoma.
Among the inhibitors of the Hh pathway that interact directly with SMO, vismodegib and sonidegib are the two compounds approved by FDA in 2012 and 2015, respectively, for the treatment of basal cell carcinoma (BCC).
2016 March 3, “Novel Acylguanidine Derivatives Targeting Smoothened Induce Antiproliferative and Pro-Apoptotic Effects in Chronic Myeloid Leukemia Cells”, in PLOS ONE, →DOI
Origin
Formed with -degib.
Full word history & related roots →Cite this entry
APA
vismodegib. (n.d.). In WatkinsX Dictionary. Retrieved November 3, 2026, from https://dictionary.watkinsx.com/word/vismodegib
MLA
“vismodegib.” WatkinsX Dictionary, https://dictionary.watkinsx.com/word/vismodegib. Accessed November 3, 2026.
Chicago
WatkinsX Dictionary, s.v. “vismodegib,” accessed November 3, 2026, https://dictionary.watkinsx.com/word/vismodegib.
Source: vismodegib on Wiktionary, CC BY-SA 4.0.