zalcitabine

Z10A1L1C3I1T1A1B3I1N1E1
UK/zalˈsɪt.ə.biːn/US/zælˈsaɪ.təˌbin/US/zælˈsɪt.əˌbin/

noun

A drug C₉H₁₃N₃O₃ which inhibits the replication of HIV and is formerly used in the treatment of AIDS, especially in combination with zidovudine. It is a synthetic analog of a pyrimidine nucleoside, acting as a reverse transcriptase inhibitor.

Similar
dideoxycytosineddC
RareScrabble 24

Meanings

nounzalcitabine (countable and uncountable, plural zalcitabines)

plural zalcitabines · alternative dideoxycytidine · alternative ddC · alternative DDC

  1. countableuncountablemedicineA drug C₉H₁₃N₃O₃ which inhibits the replication of HIV and is formerly used in the treatment of AIDS, especially in combination with zidovudine. It is a synthetic analog of a pyrimidine nucleoside, acting as a reverse transcriptase inhibitor.

    Patients received 600 mg/day of ritonavir (Abbott Laboratories) for 14 days, after which were added 600 mg/day of zidovudine (Retrovir, Glaxo-Wellcome) and 6 mg/day of zalcitabine (Hivid, Roche) with treatment maintenance for 12 months.

    1997 July 4, B. Autran et al., “Positive Effects of Combined Antiretroviral Therapy on CD4 T Cell Homeostasis and Function in Advanced HIV Disease”, in Science, volume 277, number 5322, →DOI, pages 112–116

Synonyms & antonyms

nounan antiviral drug used to combat HIV infection; a nucleoside analog reverse transcriptase inhibitor (NARTI)

Similar
dideoxycytosineddC
Broader
antiviralantiviral agentantiviral drug

Synonym sets from Open English WordNet, CC BY 4.0.

Origin

From [Term?] + -citabine (“cytarabine or azacytidine derivative”).

Full word history & related roots →
Cite this entry
APA

zalcitabine. (n.d.). In WatkinsX Dictionary. Retrieved November 4, 2026, from https://dictionary.watkinsx.com/word/zalcitabine

MLA

“zalcitabine.” WatkinsX Dictionary, https://dictionary.watkinsx.com/word/zalcitabine. Accessed November 4, 2026.

Chicago

WatkinsX Dictionary, s.v. “zalcitabine,” accessed November 4, 2026, https://dictionary.watkinsx.com/word/zalcitabine.

Source: zalcitabine on Wiktionary, CC BY-SA 4.0.