1-methyl-4-phenylpyridinium

noun

MPP+, the active metabolite of MPTP.

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Meanings

noun1-methyl-4-phenylpyridinium (uncountable)
  1. uncountablechemistryMPP+, the active metabolite of MPTP.
    1 more example

    2006, Zhang et al, Investigative Opthamological and Visual Science http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=16384975&query_hl=14&itool=pubmed_docsum Apical uptake was higher than basolateral uptake at 37 degrees C and was decreased to 70% in the presence of NaN(3) or in the absence of extracellular Na(+). Besides alpha2-agonists, apical uptake was inhibited by verapamil, desipramine, and quinidine, but not by MPP(+) (1-methyl-4-phenylpyridinium), TEA (tetraethylammonium), decynium-22, carnitine, PHA (p-aminohippurate), alanine, or inosine.

  2. uncountablemedicineA neurotoxin that cannot cross the blood-brain barrier but which, once in contact, can destroy the dopaminergic neurons of the substantia nigra.
Cite this entry
APA

1-methyl-4-phenylpyridinium. (n.d.). In WatkinsX Dictionary. Retrieved November 5, 2026, from https://dictionary.watkinsx.com/word/1-methyl-4-phenylpyridinium

MLA

“1-methyl-4-phenylpyridinium.” WatkinsX Dictionary, https://dictionary.watkinsx.com/word/1-methyl-4-phenylpyridinium. Accessed November 5, 2026.

Chicago

WatkinsX Dictionary, s.v. “1-methyl-4-phenylpyridinium,” accessed November 5, 2026, https://dictionary.watkinsx.com/word/1-methyl-4-phenylpyridinium.

Source: 1-methyl-4-phenylpyridinium on Wiktionary, CC BY-SA 4.0.