Meanings
- uncountablemedicine1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine: a byproduct of synthetic heroin, or MPPP, which causes parkinsonian symptoms in users; and a neurotoxin that degrades into MPP+ after crossing the blood-brain barrier, which causes a degradation of the dopaminergic neurons within the substantia nigra.
1 more example
2005 Dec 29, Petzinger, et al. Journal of Neuroscience Research http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=16385585&query_hl=8&itool=pubmed_docsum The neurotoxicant 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine MPTP provides an excellent opportunity to study repair and response to injury in the basal ganglia.
Cite this entry
MPTP. (n.d.). In WatkinsX Dictionary. Retrieved November 2, 2026, from https://dictionary.watkinsx.com/word/MPTP
“MPTP.” WatkinsX Dictionary, https://dictionary.watkinsx.com/word/MPTP. Accessed November 2, 2026.
WatkinsX Dictionary, s.v. “MPTP,” accessed November 2, 2026, https://dictionary.watkinsx.com/word/MPTP.
Source: MPTP on Wiktionary, CC BY-SA 4.0.