citrullinated

comparative more citrullinated · superlative most citrullinated

1. biochemistryReacted with, or converted to, citrulline.

   It^([vimentin]) had already been described in AD (25) and is one of the most citrullinated proteins besides MBP and GFAP in WMMS.

   2020, Wolfgang Faigle et al., “Brain Citrullination Patterns and T Cell Reactivity of Cerebrospinal Fluid-Derived CD4+ T Cells in Multiple Sclerosis”, in Paulus Stefan Rommer, Martin S. Weber, Zsolt Illes, Uwe K. Zettl, editors, Multiple Sclerosis - From Bench to Bedside, Frontiers Media, page 40

   2 more examples

   Initially it has been suggested that fibrin is the most citrullinated protein in RA joints (Iobagiu et al., 2011), but now the presence of citrullinated vimentin and aggrecan is also detected (Glant et al., 2016).

   2019, Geeta Rai, NETosis: Immunity, Pathogenesis and Therapeutics, Elsevier (Academic Press), page 106

   2019, Venkatesh V. Nemmara, Paul R. Thompson, Development of Activity-Based Proteomic Probes for Protein Citrullination, Benjamin F. Cravatt, Ku-Lung Hsu, Eranthie Weerapana (editors), Activity-Based Protein Profiling, Springer, page 244, Given that aberrant citrullination is a hallmark of various autoimmune diseases and certain tumor types, it is important to develop protein detection methods to identify citrullinated proteins in complex biological systems.

1. participlepastsimple past and past participle of citrullinate