denosumab

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UK/dɪˈnɒs.jʊ.mab/US/dɛnˈoʊ.səˌmæb/US/dəˈnɑs.jəˌmæb/

noun

A drug (trademarks Prolia and Xgera) that is a genetically engineered monoclonal antibody that reduces bone resorption and increases bone mass by inhibiting osteoclast formation and function and that is administered by injection to prevent fractures associated with osteoporosis and malignant tumors of bone and to treat hypercalcemia associated with various cancers.

Scrabble 14

Meanings

noundenosumab (uncountable)
  1. uncountablemedicineA drug (trademarks Prolia and Xgera) that is a genetically engineered monoclonal antibody that reduces bone resorption and increases bone mass by inhibiting osteoclast formation and function and that is administered by injection to prevent fractures associated with osteoporosis and malignant tumors of bone and to treat hypercalcemia associated with various cancers.

Origin

From arbitrary prefix den- + -os- (“bone”) + -umab (“human monoclonal antibody”).

Full word history & related roots →
Cite this entry
APA

denosumab. (n.d.). In WatkinsX Dictionary. Retrieved November 3, 2026, from https://dictionary.watkinsx.com/word/denosumab

MLA

“denosumab.” WatkinsX Dictionary, https://dictionary.watkinsx.com/word/denosumab. Accessed November 3, 2026.

Chicago

WatkinsX Dictionary, s.v. “denosumab,” accessed November 3, 2026, https://dictionary.watkinsx.com/word/denosumab.

Source: denosumab on Wiktionary, CC BY-SA 4.0.