hyperfractionation

noun

An especially highly divided form of fractionation: the division of a total dose of radiation into many small fractions.

Scrabble 31

Meanings

nounhyperfractionation (uncountable)
  1. uncountableradiotherapyAn especially highly divided form of fractionation: the division of a total dose of radiation into many small fractions.
    1 more example

    Treatment with several doses per day offers the prospect of a significant therapeutic gain using readily available low LET beams. These regimens can be classified as either accelerated fractionation or hyperfractionation according to their rationales. With accelerated fractionation a conventional number of dose fractions is delivered in a significantly shortened overall treatment time in order to reduce the opportunity for tumor cell regeneration during treatment. With hyperfractionation, on the other hand, a large number of significantly reduced dose fractions is used to give a greater total dose in a conventional overall treatment time.

    1983, H.D. Thames Jr, L.J. Peters, H.R. Withers, G.H. Fletcher, “Accelerated fractionation vs hyperfractionation: rationales for several treatments per day”, in International Journal of Radiation Oncology, Biology, Physics, volume 9, number 2, →DOI, →PMID, pages 127–138

Origin

International scientific vocabulary, from hyper- + fractionation = hyper- + fraction + -ation.

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Rhymes & wordplay

Rhymes with hyperfractionation

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Cite this entry
APA

hyperfractionation. (n.d.). In WatkinsX Dictionary. Retrieved November 3, 2026, from https://dictionary.watkinsx.com/word/hyperfractionation

MLA

“hyperfractionation.” WatkinsX Dictionary, https://dictionary.watkinsx.com/word/hyperfractionation. Accessed November 3, 2026.

Chicago

WatkinsX Dictionary, s.v. “hyperfractionation,” accessed November 3, 2026, https://dictionary.watkinsx.com/word/hyperfractionation.

Source: hyperfractionation on Wiktionary, CC BY-SA 4.0.