loperamide

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UK/ləʊˈpɛ.ɹə.mʌɪd/US/loʊˈpɛɹ.əˌmaɪd/

noun

A synthetic antidiarrheal agent of the opiate class (trademark Imodium) that slows intestinal peristalsis and is taken orally in the form of its hydrochloride C₂₉H₃₃ClN₂O₂·HCl to control acute nonspecific diarrhea or chronic diarrhea associated with inflammatory bowel disease or to reduce fecal volume discharged from ileostomies.

OriginEnglish amide ← Proto-Indo-European *dʰeh₁- ← Latin ammoniacus →
UncommonScrabble 15
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Meanings

nounloperamide (uncountable)
  1. uncountablemedicineA synthetic antidiarrheal agent of the opiate class (trademark Imodium) that slows intestinal peristalsis and is taken orally in the form of its hydrochloride C₂₉H₃₃ClN₂O₂·HCl to control acute nonspecific diarrhea or chronic diarrhea associated with inflammatory bowel disease or to reduce fecal volume discharged from ileostomies.

Origin

  1. Proto-Indo-European*ǵʰelh₃-
  2. Proto-Indo-European*ǵʰl̥h₃rós
  3. Proto-Hellenic*kʰlōrós
  4. Ancient Greekχλωρός (khlōrós)
  5. English(ch)lo(ro)-
  6. Ancient Greekπέπερῐ (péperĭ)
  7. Latinpiper
  8. English(pi)per(idine)
  9. Egyptianjmn
  10. Ancient GreekᾸ̓́μμων (Ắmmōn)
  11. LatinAmmōn
  12. Latinammoniacus
  13. Englishammonia
  14. Proto-Indo-European*dʰeh₁-
  15. Englishamide
  16. Englishloperamide

From (ch)lo(ro)- + (pi)per(idine) + -amide.

Full word history & related roots →

Rhymes & wordplay

Anagrams

perameloid
Cite this entry
APA

loperamide. (n.d.). In WatkinsX Dictionary. Retrieved November 2, 2026, from https://dictionary.watkinsx.com/word/loperamide

MLA

“loperamide.” WatkinsX Dictionary, https://dictionary.watkinsx.com/word/loperamide. Accessed November 2, 2026.

Chicago

WatkinsX Dictionary, s.v. “loperamide,” accessed November 2, 2026, https://dictionary.watkinsx.com/word/loperamide.

Source: loperamide on Wiktionary, CC BY-SA 4.0.