nocebo

no·ce·bo
N1O1C3E1B3O1
UK/nəʊˈsiː.bəʊ/US/noʊˈsi.boʊ/

noun

A substance which a patient experiences as harmful due to a previous negative perception, but which is in fact pharmacologically (medicinally) inactive.

“The nocebo effect is considered by some as the direct inverse of the placebo effect.”

First used 1961Scrabble 10

Meanings

nounnocebo (plural nocebos)

plural nocebos

  1. alsoattributivemedicineA substance which a patient experiences as harmful due to a previous negative perception, but which is in fact pharmacologically (medicinally) inactive.First known use 1961

    The nocebo effect is considered by some as the direct inverse of the placebo effect.

    4 more examples

    It is somewhat surprising that little attention has been drawn to the existence of the contrary effect [to the placebo] – which I may call the nocebo reaction.

    1961 September, Walter P. Kennedy, “The Nocebo Reaction”, in Medical World, volume 95, London: Medical Practitioners' Union, →ISSN, →OCLC, →PMID, page 203

    In the case of the nocebo, it is negative expectations that become self-fulfilling prophecies.

    2009 April 25, Stuart Blackman, “Why health warnings can be bad”, in Financial Times

    It seems to be a "nocebo" effect – the self-diagnosed gluten sensitive patients expected to feel worse on the study diets, so they did.

    2014 May 15, Jennifer Welsh, “Researchers who Provided Key Evidence for Gluten Sensitivity have now Thoroughly Shown that It Doesn’t Exist”, in Business Insider, archived from the original on 02 Jul 2017

    If there's one lesson to be drawn from the nocebo effect, it's that ideas are never merely ideas. […] Maybe you see where I'm going with this: our grim view of humanity is also a nocebo.

    2020, Rutger Bregman, Humankind, Bloomsbury Publishing, →ISBN

Origin

  1. Latinnocēbō“I will harm”
  2. Englishnocebo

Borrowed from Latin nocēbō (“I will harm”), the first-person singular future active indicative form of noceō (“to harm”), by analogy with placebo. The word was coined by Walter P. Kennedy in an article entitled “The Nocebo Reaction” (1961). (see quotation).

Full word history & related roots →

Translations

Czech nocebo
  • noceboa pharmacologically inactive substance experienced as harmful
Danish nocebo
  • noceboa pharmacologically inactive substance experienced as harmful
Dutch nocebo
  • noceboa pharmacologically inactive substance experienced as harmful
Finnish nosebo
  • noseboa pharmacologically inactive substance experienced as harmful
German Nocebo
  • Noceboa pharmacologically inactive substance experienced as harmful
Indonesian nocebo
  • noceboa pharmacologically inactive substance experienced as harmful
Italian nocebo
  • noceboa pharmacologically inactive substance experienced as harmful
Korean 노시보
  • 노시보 (nosibo)a pharmacologically inactive substance experienced as harmful
Norwegian nocebo
  • noceboa pharmacologically inactive substance experienced as harmful
Polish nocebo
  • noceboa pharmacologically inactive substance experienced as harmful
Portuguese nocebo
  • noceboa pharmacologically inactive substance experienced as harmful
Russian ноцебо
  • ноцебо (nocebo)a pharmacologically inactive substance experienced as harmful
Spanish nocebo
  • noceboa pharmacologically inactive substance experienced as harmful
Swedish nocebo
  • noceboa pharmacologically inactive substance experienced as harmful
Turkish nocebo
  • noceboa pharmacologically inactive substance experienced as harmful
Ukrainian ноцебо
  • ноцебо (nocebo)a pharmacologically inactive substance experienced as harmful
Vietnamese nocebo
  • noceboa pharmacologically inactive substance experienced as harmful

Rhymes & wordplay

Rhymes with nocebo

All rhymes →
Cite this entry
APA

nocebo. (n.d.). In WatkinsX Dictionary. Retrieved November 3, 2026, from https://dictionary.watkinsx.com/word/nocebo

MLA

“nocebo.” WatkinsX Dictionary, https://dictionary.watkinsx.com/word/nocebo. Accessed November 3, 2026.

Chicago

WatkinsX Dictionary, s.v. “nocebo,” accessed November 3, 2026, https://dictionary.watkinsx.com/word/nocebo.

Source: nocebo on Wiktionary, CC BY-SA 4.0.