nucleosome

N1U1C3L1E1O1S1O1M3E1

noun

Any of the subunits that repeat in chromatin; a coil of DNA surrounding a core of eight histones.

UncommonScrabble 14

Meanings

nounnucleosome (plural nucleosomes)

plural nucleosomes

  1. biologyAny of the subunits that repeat in chromatin; a coil of DNA surrounding a core of eight histones.

    We have termed these particles “nucleosomes,” to evoke their nuclear origin and their resemblance to the “nu” (ν) bodies described by Olins and Olins (1974).

    1975, P. Oudet, M. Gross-Bellard, P.Champon, “Electron Microscopic and Biochemical Evidence that Chromosome Structure Is a Repeating Unit”, in Cell, →PMID, page 9

Origin

From nucleo- + -some, and to evoke the older name nu body. Coined by P. Oudet et al. in 1975 (see quotation below).

Full word history & related roots →

Translations

French nucléosome
  • nucléosomerepeating subunit in chromatin
German Nukleosom
  • Nukleosomrepeating subunit in chromatin
Italian nucleosoma
  • nucleosomarepeating subunit in chromatin
Korean 뉴클레오솜
  • 뉴클레오솜 (nyukeulle'osom)repeating subunit in chromatin
Spanish nucleosoma
  • nucleosomarepeating subunit in chromatin
Swedish nukleosom
  • nukleosomrepeating subunit in chromatin
Cite this entry
APA

nucleosome. (n.d.). In WatkinsX Dictionary. Retrieved November 4, 2026, from https://dictionary.watkinsx.com/word/nucleosome

MLA

“nucleosome.” WatkinsX Dictionary, https://dictionary.watkinsx.com/word/nucleosome. Accessed November 4, 2026.

Chicago

WatkinsX Dictionary, s.v. “nucleosome,” accessed November 4, 2026, https://dictionary.watkinsx.com/word/nucleosome.

Source: nucleosome on Wiktionary, CC BY-SA 4.0.