nucleotide

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/ˈn(j)u(ː)kliəˌtaɪd/US/ˈn(j)u(ː)klioʊˌtaɪd/

noun

The monomer constituting DNA or RNA biopolymer molecules. Each nucleotide consists of a nitrogenous heterocyclic base (or nucleobase), which can be either a double-ringed purine or a single-ringed pyrimidine; a five-carbon pentose sugar (deoxyribose in DNA or ribose in RNA); and a phosphate group.

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CommonScrabble 13

Meanings

nounnucleotide (plural nucleotides)

plural nucleotides

  1. biochemistryThe monomer constituting DNA or RNA biopolymer molecules. Each nucleotide consists of a nitrogenous heterocyclic base (or nucleobase), which can be either a double-ringed purine or a single-ringed pyrimidine; a five-carbon pentose sugar (deoxyribose in DNA or ribose in RNA); and a phosphate group.

    Magid draws […] a diagram depicting a restriction enzyme cutting neatly through a sequence of nucleotides.

    2000, Zadie Smith, White Teeth, London: Penguin Books, published 2001, →ISBN, page 464
    1 more example

    With a genome of only 400 million or so nucleotide bases, the pufferfish, Fugu rubripes rubripes, has the smallest known genome of any vertebrate animal. […] But the region of DNA between the landmarks can be a million or more nucleotides long.

    1993 December 28, James Younger, “Fishy Short Cut To Mapping Human Genome”, in The New York Times

Synonyms & antonyms

nouna phosphoric ester of a nucleoside; the basic structural unit of nucleic acids (DNA or RNA)

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Broader

Synonym sets from Open English WordNet, CC BY 4.0.

Origin

  1. Proto-Italic*knuks
  2. Latinnux
  3. Latinnucleu
  4. Englishnucleus
  5. Englishnucleo-
  6. Proto-Indo-European*dʰeh₁-
  7. Englishnucleotide

From nucleo- (“relating to the nucleus”) + -ide (“chemical suffix”).

Full word history & related roots →

Translations

Catalan nucleòtid
  • nucleòtidmonomer constituting DNA or RNA
Chinese Cantonese 核苷酸
  • 核苷酸 (hat⁶ gam¹ syun¹)monomer constituting DNA or RNA
Chinese Mandarin 核苷酸
  • 核苷酸 (hégānsuān)monomer constituting DNA or RNA
Czech nukleotid
  • nukleotidmonomer constituting DNA or RNA
Esperanto nukleotido
  • nukleotidomonomer constituting DNA or RNA
Finnish nukleotidi
  • nukleotidimonomer constituting DNA or RNA
French nucléotide
  • nucléotidemonomer constituting DNA or RNA
German Nukleotid
  • Nukleotidmonomer constituting DNA or RNA
Greek νουκλεοτίδιο
  • νουκλεοτίδιο (noukleotídio)monomer constituting DNA or RNA
Hungarian nukleotid
  • nukleotidmonomer constituting DNA or RNA
Icelandic kirni, núkleótíð
  • kirnimonomer constituting DNA or RNA
  • núkleótíðmonomer constituting DNA or RNA
Indonesian nukleotida
  • nukleotidamonomer constituting DNA or RNA
Italian nucleotide
  • nucleotidemonomer constituting DNA or RNA
Japanese ヌクレオチド
  • ヌクレオチド (nukureochido)monomer constituting DNA or RNA
Korean 뉴클레오티드
  • 뉴클레오티드 (nyukeulle'otideu)monomer constituting DNA or RNA
Māori pūiokarihi
  • pūiokarihimonomer constituting DNA or RNA
Polish nukleotyd
  • nukleotydmonomer constituting DNA or RNA
Portuguese nucleotídeo
  • nucleotídeomonomer constituting DNA or RNA
Romanian nucleotidă
  • nucleotidămonomer constituting DNA or RNA
Russian нуклеоти́д
  • нуклеоти́д (nukleotíd)monomer constituting DNA or RNA
Spanish nucleótido
  • nucleótidomonomer constituting DNA or RNA
Swedish nukleotid
  • nukleotidmonomer constituting DNA or RNA
Turkish nükleotit
  • nükleotitmonomer constituting DNA or RNA
Ukrainian нуклеоти́д
  • нуклеоти́д (nukleotýd)monomer constituting DNA or RNA
Cite this entry
APA

nucleotide. (n.d.). In WatkinsX Dictionary. Retrieved November 3, 2026, from https://dictionary.watkinsx.com/word/nucleotide

MLA

“nucleotide.” WatkinsX Dictionary, https://dictionary.watkinsx.com/word/nucleotide. Accessed November 3, 2026.

Chicago

WatkinsX Dictionary, s.v. “nucleotide,” accessed November 3, 2026, https://dictionary.watkinsx.com/word/nucleotide.

Source: nucleotide on Wiktionary, CC BY-SA 4.0.