deplete

D2E1P3L1E1T1E1
UK/dɪˈpliːt/US/dɪˈplit/US/diˈplit/US/dəˈplit/

verb

To reduce the amount of; to remove (a substance from something)

“Certain medications can deplete vitamin D.”

UncommonScrabble 10

Meanings

verbdeplete (third-person singular simple present depletes, present participle depleting, simple past and past participle depleted)

present singular third person depletes · participle present depleting · participle past depleted · past depleted

  1. transitiveTo reduce the amount of; to remove (a substance from something)

    The winter storm quickly depleted the salt supply of the county.

    3 more examples

    Their numbers have been very heavily depleted in the last few years, and soon a most familiar part of the southern railway scene will have vanished: […].

    1954 May, John W. Grant, “A Railway Requiem”, in Railway Magazine, page 352

    ... depleting the minerals and fuels of the more developed states, leading to a scarcity of these crucial resources.

    1975, William Roscoe Kintner, Harvey Sicherman, Technology and International Politics: The Crisis of Wishing

    [page 1-54:] Here [in Gabon ...], concentrations of slightly enriched uranium were deposited as sediments in a stream bed and formed seven separate water moderated reactors which operated for thousands of years, depleting the uranium and producing fission products, plutonium and other actinides.

    1982, Are Current Emergency Planning Requirements Justified?: Workshop Proceedings
  2. To reduce the amount of; to remove (a substance from something):
    1. transitivechemistryTo expend or separate a reactant.
    2. transitivemedicineTo reduce the amount of a substance with a medication or medical procedure or due to a illness.

      Certain medications can deplete vitamin D.

    3. transitiveTo use up, exhaust, or consume (power or resources).

      Its reserves have been invaded and depleted.

      2007, John Zerzan, Silence
      1 more example

      Constant vigilance for social threats and the negative emotions it produces (e.g., anxiety) deplete self-regulatory resources.

      2022 October 25, L. J. Shrum, Elena Fumagalli, Tina M. Lowrey, “Coping with loneliness through consumption”, in Journal of Consumer Psychology, volume 33, number 2, →DOI, pages 441–465
    4. raretransitivenatural sciencesTo decrease the amount of an isotope (in a mixture of isotopes).

      Antonyms: enrich

  3. transitiveTo empty or purge (something of a substance).

    This drug can deplete the body of magnesium.

    3 more examples

    The conservation project depleted the lake of algae.

    However, every Practitioner ought to be appriz'd of a ſtanding Truth in all Coughs of this Kind, that ſome proper Evacuations ought to precede, in order to revulſe the Motion from the Lungs to ſome distant Goal, as well as to deplete the Veſſels of ſuch a troubleſome Lodger.

    1716, [John Radcliffe], “Electuarium Phthiſicum”, in Pharmacopœia Radcliffeana: or, Dr. Radcliff's Preſcriptions, second corrected edition, London: Charles Rivington, page 22

    ... deplete the body of minerals, causing osteoporosis.

    2005, Teresa Cutter, The 80/20 Diet: 12 Weeks to a Better Body, Allen & Unwin, →ISBN, page 21
    1. transitivechemistryTo clear a compound or solution (of a reactant).

      Cycling also produces layered scales, as repeated spallation further depletes the compound of Al and allows Cr₂O₃ formation.

      2017 February 28, James L. Smialek, “Cr₂AlC Issues: Scale Adhesion”, in Unusual oxidative limitations for Al-MAX phases (NASA technical memorandum; 2017-219444), Cleveland, Ohio: NASA, →OCLC, page 15
    2. transitivenatural sciencesTo clear a mixture of isotopes (of an isotope or isotopes).

      The by-product of this process, which depletes uranium of its most radioactive isotopes, is called depleted uranium (DU).

      1999, Naomi H. Harley [et al.], A Review of the Scientific Literature As It Pertains to Gulf War Illnesses, volume 7: Depleted Uranium, Santa Monica, CA: RAND, →ISBN, →OCLC, page xiii

      Antonyms: enrich

  4. intransitiveTo diminish in quantity or strength; to be consumed.

    I noticed a couple of days ago how quickly the battery depletes.

    2 more examples

    Depending on what you print, one color usually depletes faster than the others.

    He said that if I could not urinate within the next few hours I would be charged with refusing to comply with an order and be punished. In spite of my inability to eat much due to my depleted physical condition, I drank as much as I could and still was unable to urinate within the prescribed time.

    1989 December 17, Edward Inman, “Disobeying An Order To Piss Lands Transsexual In Isolation”, in Gay Community News, volume 17, number 23, page 5
    1. intransitivechemistryTo be expended or separated (of a substance).

      As can be seen in Fig. 1.49, FS 21 rapidly depletes of Li⁺ near the surface during the exposure to a NaNO₃ melt and simultaneously enriches in Na⁺.

      2008 June 24, Dagmar Hülsenberg, Alf Harnisch, Alexander Bismarck, “1. Silicate Glasses: A Class of Amorphous Materials”, in Microstructuring of Glasses, Berlin: Springer Science+Business Media, →DOI, →ISBN, →OCLC, page 54
    2. intransitivenatural sciencesTo undergo loss of an isotope.

      Since uranium depletes in this process, it is called fissile fuel, nuclear fuel or simply fuel.

      2025 February 10, Farid Gamgami, “11. Nuclear Propulsion Technology and Systems”, in Space Propulsion and Spaceship Design: A System Perspective, Berlin: Springer Science+Business Media, →DOI, →ISBN, →OCLC, page 54

Synonyms & antonyms

verbTo decrease the amount of an isotope (in a mixture of isotopes).

Opposite

verbTo clear a mixture of isotopes (of an isotope or isotopes).

Opposite
Opposite

More synonyms by meaning

verbuse up (resources or materials)

Synonym sets from Open English WordNet, CC BY 4.0.

Origin

  1. Latindēplētus“empty”
  2. Englishdeplete

Borrowed from Latin dēplētus (“empty”), from depleō. First attested in 1716; originally a medical term.

Full word history & related roots →

Translations

Bulgarian изпразвам, изчерпвам
  • изпразвам (izprazvam)reduce the amount of or remove
  • изчерпвам (izčerpvam)reduce the amount of or remove
Chinese Mandarin 耗竭, 放血
  • 耗竭 (hàojié)reduce the amount of or remove
  • 放血 (fàngxuè)reduce the amount of or remove
Dutch leegmaken, opruimen
  • leegmakenreduce the amount of or remove
  • opruimenreduce the amount of or remove
  • afbrekenreduce the amount of or remove
Finnish tyhjetä, kulua
  • tyhjetäreduce the amount of or remove
  • kuluareduce the amount of or remove
  • tyhjentääreduce the amount of or remove
  • kuluttaareduce the amount of or remove
French vider
  • viderreduce the amount of or remove
German leeren, räumen
  • leerenreduce the amount of or remove
  • räumenreduce the amount of or remove
  • aufbrauchenreduce the amount of or remove
Greek εκκενώνω, αδειάζω
  • εκκενώνω (ekkenóno)reduce the amount of or remove
  • αδειάζω (adeiázo)reduce the amount of or remove
Hungarian kiürít, kimerít
  • kiürítreduce the amount of or remove
  • kimerítreduce the amount of or remove
Indonesian menguras, mengosongkan
  • mengurasreduce the amount of or remove
  • mengosongkanreduce the amount of or remove
Latin exhauriō
  • exhauriōreduce the amount of or remove
Portuguese exaurir, esgotar
  • exaurirreduce the amount of or remove
  • esgotarreduce the amount of or remove
  • esvaziarreduce the amount of or remove
Russian очища́ть, производи́ть кровопуска́ние
  • очища́ть (očiščátʹ)reduce the amount of or remove
  • производи́ть кровопуска́ние (bloodletting)reduce the amount of or remove
Spanish depletar, mermar
  • depletarreduce the amount of or remove
  • mermarreduce the amount of or remove
  • agotarreduce the amount of or remove
  • depletearreduce the amount of or remove
  • deplecionarreduce the amount of or remove

Rhymes & wordplay

Rhymes with deplete

All rhymes →
Cite this entry
APA

deplete. (n.d.). In WatkinsX Dictionary. Retrieved November 3, 2026, from https://dictionary.watkinsx.com/word/deplete

MLA

“deplete.” WatkinsX Dictionary, https://dictionary.watkinsx.com/word/deplete. Accessed November 3, 2026.

Chicago

WatkinsX Dictionary, s.v. “deplete,” accessed November 3, 2026, https://dictionary.watkinsx.com/word/deplete.

Source: deplete on Wiktionary, CC BY-SA 4.0.