sertraline

S1E1R1T1R1A1L1I1N1E1
UK/ˈsɜː.tɹəˌliːn/US/ˈsɜɹ.tɹəˌlin/

noun

An antidepressant drug C₁₇H₁₇NCl₂ administered in the form of its hydrochloride and acting to enhance serotonin activity.

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Meanings

nounsertraline (uncountable)
  1. uncountablemedicineAn antidepressant drug C₁₇H₁₇NCl₂ administered in the form of its hydrochloride and acting to enhance serotonin activity.

    Sertraline, 50 mg. Insomnia worsened, severe anxiety, anorexia, (weight loss 17kgs,) increase in suicidal thougts, plans, and intention. Discontinued following hospitalization.

    2002, Sarah Kane, 4.48 Psychosis, Methuen, →ISBN, page 21

    Synonyms: Zoloft

Synonyms & antonyms

nounAn antidepressant drug C₁₇H₁₇NCl₂ administered in the form of its hydrochloride and acting to enhance serotonin activity.

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More synonyms by meaning

nouna selective-serotonin reuptake inhibitor commonly prescribed as an antidepressant (trade name Zoloft)

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Broader
selective-serotonin reuptake inhibitorSSRI
Also see

Synonym sets from Open English WordNet, CC BY 4.0.

Origin

From ser(otonin) + -traline (“serotonin reuptake inhibitor”).

Full word history & related roots →

Translations

French sertraline
  • sertralinethe antidepressant
Japanese セルトラリン
  • セルトラリン (serutorarin)the antidepressant
Portuguese sertralina
  • sertralinathe antidepressant
Spanish sertralina
  • sertralinathe antidepressant
Cite this entry
APA

sertraline. (n.d.). In WatkinsX Dictionary. Retrieved November 4, 2026, from https://dictionary.watkinsx.com/word/sertraline

MLA

“sertraline.” WatkinsX Dictionary, https://dictionary.watkinsx.com/word/sertraline. Accessed November 4, 2026.

Chicago

WatkinsX Dictionary, s.v. “sertraline,” accessed November 4, 2026, https://dictionary.watkinsx.com/word/sertraline.

Source: sertraline on Wiktionary, CC BY-SA 4.0.